Caring for patients with XLH requires a multidisciplinary approach

The goals of treatment are:

In Children

• Mitigate the progression of rickets in infants that have been diagnosed even before rachitic features manifest³
• Augment growth through growth hormone supplementation³
• In older children, correct leg abnormalities through surgeries, and facilitate the mineralization of the bones and teeth; phosphate and calcitriol may be beneficial depending on individualized goals^2,3
• Encourage extensive dental care for the management of dental abscesses^2,3

In Adults

• Reduction of pain and stiffness of the bones, muscles, and joints from osteoarthritis³
• Corrective surgeries and other procedures that address underlying fractures, pseudofractures, and enthesopathies⁴
• Promotion of bone mineralization through phosphate and calcitriol supplements for adult patients with planned surgeries (osteotomies and dental implants)^2,3
• Extensive dental care for the management of dental abscesses and periodontitis; tooth extractions may be needed^2,3

For patients with X-linked dominant disorders like XLH, genetic counselling can be an important element in helping patients:

• manage their condition;
• identify family members at risk; and
• think about family planning.

You can access no-charge genetic counselling for your patients with XLH.